usps overnight shipping cutoff time USPS overnight shipping cutoff times vary depending on the location and the specific post office. Generally, USPS accepts Priority Mail Express shipments until 5:00 PM for most locations, but cutoff times may be earlier in some areas. It is recommended to check with your local USPS office for specific cutoff times to ensure your package is processed and shipped the same day. For urgent shipments, using the correct cutoff time is essential to guarantee overnight delivery.